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prsW [2018-03-18 12:23:23]
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prsW [2018-03-18 12:23:23]

protease, cleaves RsiW in the presence of antimicrobial peptides
locus
BSU22940
pI
8.09
mw
24.57 kDa
protein length
218 aa Sequence Blast
gene length
654 bp Sequence Blast
function
control of SigW activity
product
protease
essential
no
synonyms
ypdC
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.7|Proteolysis] → [category|SW 3.3.7.4|Additional proteins involved in proteolysis]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.1|Sigma factors and their control] → [category|SW 3.4.1.2|Control of sigma factors]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    2,400,208 → 2,400,864

    The protein

    Protein family

  • protease prsW family (according to Swiss-Prot)

    • [SW|Localization]

  • membrane [Pubmed|17020587]

    • Expression and Regulation

    Operons

    genes
    [gene|EE3B6B52EA19958E2E46A1545747F5209A6AA036|prsW]
    description
    [Pubmed|22383849]
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    Biological materials

    Mutant

  • MGNA-A418 (ypdC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/418 NBRP B. subtilis, Japan]
  • BKE22940 (Δ[gene|EE3B6B52EA19958E2E46A1545747F5209A6AA036|prsW]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE22940 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCAGGCAACCTCTTTCCT, downstream forward: _UP4_TAGAAGCCGCACAGCAACCG
  • BKK22940 (Δ[gene|EE3B6B52EA19958E2E46A1545747F5209A6AA036|prsW]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK22940 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCAGGCAACCTCTTTCCT, downstream forward: _UP4_TAGAAGCCGCACAGCAACCG

    • Labs working on this gene/protein

  • [SW|Thomas Wiegert], University of Bayreuth, Germany [http://www.genetik.uni-bayreuth.de/LSGenetik1/Thomas%20Wiegert-Dateien/Thomas%20Wiegert.html Homepage]

    • References

    Reviews

  • 22688815,23479438,22381678

    • Original publications

  • 16816000,17020587,19889088,23155385